About ILUVIEN – Designed by Ophthalmologists for Ophthalmologists
Together, chemistry and technology enable long-acting, continuous, low dose, steroid release with ILUVIEN for up to 36 months1
1. Habib MS. Ther Deliv 2018;
The ILUVIEN Implant
The external capsule is made from polyimide, an inert material used in the haptics of intra-ocular lenses.
ILUVIEN has a non-permeable plug at one end. At the other end is a permeable membrane made of poly-vinyl alcohol (PVA) that allows the molecular passage of fluocinolone acetonide.
The internal part of the implant consists of a PVA matrix + fluocinolone acetonide molecules.
CONTINUOUS MICRODOSING Technology
ILUVIEN CONTINUOUS MICRODOSING results in zero order kinetics with stable steroid release for up to 3 years. Whilst most drugs are eliminated via first-order kinetics2, elimination with ILUVIEN is time rather than concentration dependent from approximately 6 months after administration1
Aqueous levels of Fluocinolone acetonide in human eyes1
FAc = Flucocinolone acetonide
Data presented as mean ± standard error
1. ILUVIEN, Summary of Product Characteristics.
2. Campochiaro PA, Brown DM, et al. Ophthalmology 2011; 118: 626-635.
Unique Delivery System
ILUVIEN’s applicator has a 25 gauge needle, which produces a self-sealing wound, with no need for a tunnelling procedure. The injection is simple and is performed at 4 mm inferotemporal from the limbus. As there is no spring in the device, the implant is “smoothly” delivered into the posterior part of the eye, where it settles in the vitreous and starts releasing the fluocinolone acetonide (FAc).
Leave the ILUVIEN UK site?
The link you have selected is not under the review or control of Alimera Sciences and, as such, the company does not endorse the content, its accuracy, or any practices or standards contained within it.
Please confirm if you wish to follow this link.
Leave the ILUVIEN UK site?
The link you have selected is not under the review or control of Alimera Sciences and, as such, the company does not endorse the content, its accuracy, or any practices or standards contained within it.
Please confirm if you wish to follow this link.